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The winners will be the assets that close it: either via oral formulations that improve adherence (ASC37, SP-2297, Rani), via long-interval dosing that reduces attrition (monthly ASC37 SC, Fc-fusion MWN-101/ZX2021), via better tolerability ratios (small-molecule HM-15275), or via combination formulations that add amylin or calcitonin effects on top of the triple agonist (AstraZeneca's combination-centric patent position is the early signal of this thesis)
Semaglutide (Wegovy) is the newest FDA-approved medication for chronic weight management
for decades
The lack of transparency means we still dont have vetted safety data from a controlled trial
La Fleurs research aims to unravel the mechanistic link between diet composition and the development of obesity and diabetes as a first step towards a better understanding of the pathogenesis of Diabetes Type 2, focussing on the role of the brain
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