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In addition, large-scale clinical trials have consistently reported their benefits in cardiovascular disease and diabetic kidney disease
Wei Z, Li X, Zhou J, Zhou Y, Xiao Z, Yang Q
10.1016/S0006-8993(02)04087-8 Brain Res
The underlying mechanisms for increased HR remain to be fully elucidated, but may be related to a direct GLP-1 receptor effect on myocytes in the sinoatrial node of the human heart and/or stimulation of the sympathetic nervous system
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