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3.2 Regulating lipid metabolism to relieve NAFLD 3.2.1 Core pathological process The main cause of NAFLD is the excessive accumulation of fat in the liver (Kanuri and Bergheim, 2013

10.3892/etm.2019.7282 66 SymondsJ

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Both the thioredoxin (Trx) and GSH-dependent glutaredoxin (Grx) antioxidant systems have been found to reduce methionine sulfoxide reductases in vitro and/or in vivo (see Figure 2 ) (28)