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[4] [6] In trials, the effects of retatrutide are thought to be mediated through a combination of appetite suppression, increased energy expenditure, and broader metabolic regulation though the precise contribution of each receptor pathway in humans remains under investigation, and long-term cardiovascular and safety outcomes are not yet established

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Tesofensine Tesofensine ( NS2330 ) is a serotoninnorepinephrinedopamine reuptake inhibitor from the phenyltropane family of drugs, which is being developed for the treatment of obesity

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