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In a 6-month, randomized, double-masked, placebo-controlled study, ruboxistaurin enhanced skin microvascular blood flow at the distal calf, reduced sensory symptoms, improved the quality of life, and was well tolerated in DPN patients

Differences in categorical variables were assessed using the Chi-square test

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In mitochondria, lipid oxidation causes loss of membrane potential, increases reactive oxygen species (ROS) and promotes epithelialmesenchymal transition (EMT) (Wang et al., 2016

What You Eat and Drink Matters You know that keeping uric acid levels below 6 mg/dl helps to reduce your chance of having a gout attack