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Zepbound Results (SURMOUNT-1 Trial) The SURMOUNT-1 trial studied 2,539 adults with obesity or overweight (without diabetes) over 72 weeks
Semaglutide significantly downregulates the expression levels of key pro-inflammatory factors such as TNF-, IL-6, and IL-1 in the gastrocnemius muscle, while effectively improving IR, as evidenced by a significant reduction in the Homeostatic Model Assessment of Insulin Resistance index [28]
What to Tell Your Provider If youre on a statin and starting semaglutide, the most useful thing you can do is make sure your full lipid history and current statin regimen are part of the intake conversation
Stopping injections does not cause rebound weight gain unless you simultaneously abandon the dietary and activity changes that drove the result
Christen, T
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