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Additionally, a metaanalysis of the SUSTAIN (Efficacy and Safety of Semaglutide OnceWeekly Versus Sitagliptin OnceDaily as Addon to Metformin and/or TZD in Subjects With Type 2 Diabetes) and PIONEER (Efficacy and Safety of Oral Semaglutide Versus Placebo in Subjects With Type 2 Diabetes Mellitus Treated With Diet and Exercise Only) trials, which explored adverse events associated with semaglutide, 16 found a significantly increased risk of DVT with semaglutide

Adverse events In the STEP-1 trial, the rate of GI adverse events was 1.5 times higher in the semaglutide group vs

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