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Washington, DC: The National Academies Press

Who Is at Risk of Vitamin B12 Deficiency

By inhibiting NNMT, 5-Amino-1MQ may spare nicotinamide for NAD+ synthesis via the salvage pathway, thereby activating SIRT1 (Sirtuin 1) pathways associated with mitochondrial biogenesis, fat oxidation, and metabolic flexibility [3]

AOD-9604 is the modified 16-amino-acid version with an added N-terminal tyrosine that improves stability

Intramuscular Injection Sites For intramuscular injections, the most common sites include the deltoid muscle of the arm, the vastus lateralis muscle of the thigh, and the ventrogluteal muscle of the hip