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(a) Schematic representation of the AtNUDX23 and AtNUDX23-E169Q proteins used in this study

In a reference strain belonging to the hypervirulent ET-37 electrophoretic type (clonal complex ST-11), 93/4286, mutS was found to be inactivated by IS 1106 , while mutL allelic variants associated with high spontaneous mutation frequency were detected among isolates belonging to ET-24 electrophoretic type (lineage 3, clonal complex ST-41/44) (Colicchio et al., 2006a), supporting the idea that the activity of the DNA mismatch repair system, in particular MutL activity, is subject to a sophisticated mechanism of modulation within the species N

Raval AD et al

The overlap can be misleading