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Single Daily Dose Both once-daily and twice-daily dosing approaches have proponents in the community

Disruption of IL-24 increases cell death in APAP-stimulated mouse hepatocytes, significantly decreased levels of IL-24 in patients with clinical ALF may be associated with disease progression, thus IL-24 is a potential biological indicator of prognosis or therapeutic intervention in patients with liver injury [206]

PMID 17969590

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