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Mitochondrial ROS production and oxidative mtDNA damage is increased during reoxygenation in the GPX1 knockout mice, in addition to structural abnormalities in cardiac mitochondria and myocytes, suggesting GPX1 may play an important role in protecting cardiac mitochondria from reoxygenation damage in vivo
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Like any other payer or employer whos bearing that cost, we want to be extremely responsible, Brian Caveney, its chief medical and scientific officer, told HR Brew in February
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