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Additionally, our molecular experiments confirmed that chemotherapy drugs increase the expression levels of intracellular GSH and antioxidant enzymes, leading to chemotherapy resistance during neoadjuvant chemotherapy

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Key discussion points include: Primary indication : GLP-1 receptor agonists are prescribed for type 2 diabetes management (NICE NG28) or, in specific circumstances, weight management (NICE TA875 for semaglutide 2.4mg