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Most patients start with the lowest available dose to minimize side effects and allow the body to gradually adapt to the medication
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CVS/MedImpact, regional Blues PBMs) have analogous policies: standard BMI thresholds, diet/exercise verification, and often a requirement to try older weight-loss drugs (like phentermine or orlistat) before GLP-1 coverage
In a 2025 review, after 1,200 mg intravenously twice a week for six weeks, 37.5% of participants reported lighter skin compared with 18.7% in the placebo group, and the effect faded after about six months
It cannot remove excess loose skin, but it can help improve how skin feels and appears with consistent use
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