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Gaullier JM et al

Symptoms associated with B12 deficiency may include: Persistent fatigue or weakness Memory impairment or confusion Nerve-related issues such as numbness or tingling Mood fluctuations or depression Pale or yellowish skin A B12 deficiency can affect anyone, but older adults are particularly vulnerable

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Its proposed mechanisms involve upregulating growth factor signaling relevant to tissue repair, modulating the nitric oxide system, and influencing the gut-brain axis

Oxidative stress is involved in numerous human diseases, such as neurodegenerative disease, cancer, cardiovascular disease, inflammatory disease, immune system dysfunctions, allergy, diabetes, aging