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Concentrations of proinflammatory cytokines including TNF-, C-reactive protein (CRP), and interleukin-6 (IL-6) are increased in diabetes (Nguyen 2012

Interleukin1 (IL1) enhances endometriotic cell proliferation, decreases apoptosis, and induces the secretion of IL6 and IL8 in endometriotic tissues, leading to increased proliferation in endometriosis [14, 15]

Overall odds ratios from the random effects model (3.44) and common effect model (3.40) indicate that ROSE-010 is significantly better than a placebo ( Figure 5 )

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