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Analysis of interleukin-1 (IL-1) and interleukin-8 (IL-8) expression and release in in vitro reconstructed human epidermis for the prediction of in vivo skin irritation and/or sensitization
A medication switch should include a careful review of symptoms and dosing history
References Zhao, X., Wang, M., Wen, Z., Lu, Z., Cui, L., Fu, C., Xue, H., Liu, Y
Mechanistically, it makes sense: glutathione is central to toxin clearance, mitochondrial protection, and antioxidant defense, and the nasal route offers a practical way to bypass digestive breakdown and possibly reach brain and respiratory tissues more directly