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Animal studies have not reported serious side effects, but translating dosing to humans is tricky
This includes quick IV Vitamin B12, watching the patient closely, and being ready for any problems
Endothelial injury generated directly by intracellular viral replication and by ACE2 downregulation, exposing cells to angiotensin II in the absence of the modulator effects of angiotensin 17 (Vinciguerra et al., 2020), and vascular chronic inflammation promoting the development of tissue macrophages overloaded by cholesterol (foam cells), both increase the possibility of acquiring a severe COVID-19 infection (Vinciguerra et al., 2020
M.WormskampN
Inflammatory cytokines can cross the blood-brain barrier, activating microglial cells (the brain's resident immune cells)
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