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PIONEER 6: a cardiovascular outcomes trial (CVOT) for RYBELSUS 1,2 Objective: Confirm treatment with RYBELSUS does not result in an unacceptable increase in CV risk compared to placebo (rule out 80% excess risk) in subjects with type 2 diabetes at high risk of CV events

Researchers following the regulatory trajectory should monitor the peptide regulatory landscape for updates as trial results become available

Gastroenterology and Hepatology from Bed to Bench, 14 (1), 5966

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Some studies suggest that carnitine supplements may support weight loss and improve glucose control in people with type 2 diabetes, while other studies show little to no effect, often due to small sample sizes