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clinicians typically assess for 5% weight loss to determine treatment continuation [1] [4] Months 4-6: Continued gradual reduction with consistent use Months 6-12: Progressive weight loss approaching maximum effect Beyond 12 months: Weight maintenance phase with ongoing treatment Combining weight loss injections with resistance training and adequate protein intake (generally 1.2-1.6 grams per kilogram body weight daily, though this should be individualized, especially for patients with kidney disease) helps preserve muscle mass during weight reduction

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Report all side effects to the MHRA Yellow Card Scheme

Ann Transl Med