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In humans, immunohistochemistry using a monoclonal antibody showed that the GLP-1 receptor protein is expressed in the pancreas, in smooth muscle cells of the kidney, lung, and gastrointestinal (GI) tract, and in myocytes of the heart [16]
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The pathogenesis and the pathophysiology of sepsis is very complicated and multifaceted: numerous biological mechanisms, such as infection, inflammation, oxidative stress, immune system dysregulation, blood coagulation, endothelium dysfunction, tissue damage, elevated cellular death and/or apoptosis are involved during sepsis at tissue, cellular and molecular levels causing a damaging systemic reaction [379]
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Aug 23 2020;12(8):e9973
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