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High quality trials have demonstrated incretin-based medicines improve cardiometabolic risk factors and, in some cohorts, reduce the risk of major adverse cardiovascular events
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Also at higher doses, it acts on centers in the brain and suppresses appetite
The most common side effects of semaglutide 2.4 mg are nausea (44.2%), diarrhea (30.0%), vomiting (24.8%), and constipation (23.4%) based on STEP 1 data [6]
doi: 10.1074/jbc.M113.512046 129 NauckMADAlessioDANauckMADAlessioDA
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