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in Germany reported the efficacy and safety of a hydrolyzed collagen peptide (HCP) supplement (a commercial product called Colla Sel Pro) in improving skin health in adult female individuals in a double-blind, randomized, placebo-controlled trial using biophysical (Callegari Soft-Plus device) and skin imaging (3D) techniques [48]

In 2021, Sitohang et al., in a randomized, double-blind, placebo-controlled study, evaluated a combination antioxidant formula containing glutathione for 12 weeks on UV-induced pigmentation in women 3065 years of age in Indonesia [76]

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