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Semaglutide may be unsuitable or require additional caution in patients who: are pregnant, breastfeeding or trying to conceive have a history of pancreatitis have severe gastrointestinal disease have delayed stomach emptying have significant kidney or liver impairment use insulin or medicines that can cause hypoglycaemia have diabetic retinopathy have an active or previous eating disorder have experienced a serious allergic reaction to semaglutide already use another GLP-1 or GIP/GLP-1 medicine are due to undergo surgery, sedation or general anaesthesia These factors are not all automatic exclusions
The Phase 2 ZUPREME-1 topline results with petrelintide (a long-acting amylin analogue developed by Roche and Zealand Pharma) are generating a lot of discussion
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Can The Healing Peptide (BPC-157 Therapy) improve gut health
Laboratory monitoring of electrolytes may be warranted in specific situations, such as persistent gastrointestinal symptoms, concurrent diuretic use, kidney disease, or older age
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