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Clinical trials on semaglutide (the GLP-1 sold as Wegovy and Ozempic, for example) and tirzepatide (sold as Zepbound and Mounjaro) estimate that within a few years of starting treatment, people may experience a loss of muscle mass equal to 20 years of age-related decline
GHRP-6 was historically significant as the compound that helped identify the growth hormone secretagogue receptor (later identified as the ghrelin receptor)
PMID: 25065484
Primary care physicians are mainly concerned about overprescribing or clinically inappropriate prescribing, cited by 56% of doctors, and continuity of care such as follow-up visits, titration, and/or tapering off the medication, cited by half of physicians
