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Different species of LAB have evolved specialized mechanisms to deal with the normally encountered stress conditions in particular niches [1]

Metabolism 45:9195 Verrotti A, Cieri F, Petitti MT, Morgese G, Chiarelli F (1999) Growth hormone and IGF-I in diabetic children with and without microalbuminuria

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Since uremic animals also failed to show increases in GFR and RPF after amino acid infusion, known to enhance kidney function in healthy animals, the authors concluded that the vasodilatory eicosanoids are already maximally stimulated under baseline conditions in uremic animals and, consequently, renal reserve capacity is diminished in these animals