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In vitro experiments showed that high glucose toxicity inhibited GLP-1 secretion by enteroendothelial cells and suppressed -catenin and TCF7L2 levels, suggesting an important role for TCF4 (TCF7L2) in glucose homeostasis and type 2 diabetes development (Shen et al., 2020

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Bannwarth B, Pehourcq F: Phramacological rationale for the clinical use of paracetamol: phamacokinetic and pharmacodynamic issues

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Insulin blocks fat mobilization