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It is important to distinguish between evidence-based B12 replacement therapywhich is well-established for treating documented deficiencyand the use of lipotropic combinations, which lack robust clinical validation
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Reynolds JC, Lai RW, Woodhead JST, et al
TB-500 TB-500 is a synthetic peptide derived from thymosin beta-4
The parent protein was identified during investigations of compounds in human gastric juice that conferred protection against ulceration, and the active 15-residue fragment retained the full activity of the larger protein in subsequent characterisation studies
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