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Over 30 million people in the United States live with diabetes, with another estimated 84 million people living with prediabetes
NICE guidance provides clear recommendations for GLP-1 use, which focus exclusively on glycaemic control in type 2 diabetes (NG28) and weight management in obesity (TA875 for semaglutide, TA664 for liraglutide)
The corollary is that the temptation to increase the dose because nothing is happening yet is exactly backwards the protocol is built on consistency, and week 2 is not where you judge it
At the very least you should be able to reduce it where you hardly notice it which means your nerves are once again sending proper signals
But the additive benefit of combining them remains theoretical
