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For example, those who are candidates for Wegovy meet the FDA requirements of having a BMI (body mass index) of 30 or more or 27 or more with a weight-related complication, such as hypertension or [high cholesterol], says Tom Wadden, Ph.D., a psychologist and professor at University of Pennsylvania, in Philadelphia, who studies obesity treatments

doi:10.1097/00007890-199711270-00013

Nausea affects approximately 15-20% of patients, with vomiting (5-9%), diarrhea (8%) and abdominal pain (6-7%) also common

S-Nitrosylation of 1-antitrypsin triggers macrophages toward inflammatory phenotype and enhances intra-cellular bacteria elimination

These effects result from delayed gastric emptying and direct effects on the gastrointestinal tract