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Acta MedicaMediterranea 32:16431649 Bush AI, Tanzi RE (2008) Therapeutics for Alzheimer's disease based on the metal hypothesis

Histopathology consistently showed solar elastosis and brownish-yellow, banana-shaped fibers between degenerated collagen fibers of the papillary dermis

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Increased risk of diarrhea-predominant irritable bowel syndrome (IBS-D) Increased insulin resistance and glucose intolerance, contributing to elevated blood glucose Poor wound healing, altered taste and smell, and changes in cognitive function, particularly in older adults How common is zinc deficiency