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Notably, the STEP (Semaglutide Treatment Effect in People with obesity) trials, which specifically examined body composition, demonstrated substantial weight loss compared with placebo (NCT03548935) [53], and reductions in fat mass and visceral adipose tissue were accompanied by decreases in lean mass, although the proportion of lean mass relative to total body mass increased (NCT04074161) [54]

Number of pathways (genes) selected that are actually/truly important out of 50 pathways (1656 genes) FP: False Positives

Most patients report noticeable changes in soreness, joint comfort, or recovery timing within the first two weeks

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