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In a prospective study of T2DM patients, six months of liraglutide therapy improved diastolic function and reduced left ventricular mass index [44], while additional echocardiographic studies have reported improvements in global longitudinal strain and left ventricular mass with GLP-1 receptor agonists [45]

Additional clinical data in CABG patients suggest postoperative melatonin reduces oxidative stress and inflammatory markers and is associated with improved cardiac function, further supporting its perioperative translational relevance (127)

April 2024