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The glucagon peptide family [glucagon-like peptide-1 (GLP-1), glucose-dependent insulinotropic peptide (GIP) and glucagon] Figure 2: Simplified schematic overview of the glucagon superfamily of peptides [28] The glucagon peptide family members [GLP-1, GIP and glucagon] have similar peptide sequences, permitting the development of single-sequence multi-receptor agonists [4]

F.StubbsB.et al (2025)

The rise in cAMP activates protein kinase A (PKA), which promotes insulin exocytosis and enhances beta cell survival and proliferation

F.JrAllanC.ChanE.DavisonD.EarlsM.et al (2019)

Instead, the new carbonoxygen bonds are created by using an acyl hydroperoxide both as substrate and oxygen donor, in essence acting as a dehydratase