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7,64 For instance, CKD patients may develop low or high sodium levels due to imbalances in sodium excretion and retention

Mitochondrial dysfunction and ER stress increase ROS production, which enhances NLRP3 expression by up to 23 fold in experimental hepatocyte models, triggering caspase-1 activation and secretion of IL-1 and IL-18 [68]

Most published evidence currently comes from laboratory and animal studies, with relatively few controlled human trials available

The sleep distribution further indicates that fewer than one in three participants met the recommended eight hours or more per night, underscoring the widespread issue of short sleep in this age group

the majority (i.e., four) of these ASVs mapped to Dubosiella newyorkensis while the remaining two ASVs mapped to Romboutsia ilealis