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These metabolites spanned across five key classes: Carbohydrate Metabolomics, Nucleotide and Its Metabolites, Organic Acids and Derivatives, Phosphate Sugars, and Phosphoric Acids, suggesting a metabolic realignment in response to the redox disequilibrium induced by the absence of GR

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Cell 167 , 14691480.e1412 (2016)

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However, growing evidences in the last two decades suggest that GPx2 and GPx4 may also influence the cellular radiosensitivity in an organ-specific manner (Table 2) [54,55,56, 67]