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Longer acting GLP-1 receptor agonists and the potential for improved cardiovascular outcomes: a review of current literature
Binding of GLP-1 to GLP1R has multiple effects, including enhancing insulin secretion from pancreatic beta cells in response to glucose, increasing insulin expression, preventing beta-cell apoptosis, promoting the formation of new beta cells, reducing glucagon secretion, slowing down stomach emptying, promoting satiety, and improving glucose disposal in peripheral tissues
So, the safest message is this: GLP-1 drugs for heart protection in autoimmune disease may show promise, but patients need personalized medical advice
This pattern was evident in the case report where pain developed when the dose increased from 7.5 mg to 10 mg
10.1007/s12035-022-02934-z 30
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