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Weight loss through lifestyle interventions clearly improves metabolic factors associated with obesity as well as conditions coexisting with obesity, warranting its use as a first-line treatment
Agents such as quercetin, jujuboside A, cornuside, boeravinone C, cycloastragenol, and the JinChan YiShen TongLuo formula have been demonstrated to block TECs apoptosis through modulating mitochondrial function, ER stress, or key signaling pathways (117, 120, 128131), exhibiting promising translational potential
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