Injection-Site Reactions: Mild redness, swelling, or discomfort may occur at the injection site
Source: Barrett, et al JAMA Surgery, September 17, 2025 Researchers correlated insurance claims data and electronic medical records in a system that owns both an insurance plan (Highmark) and a provider system (Allegheny Health), and compared total medical expense for over 30,000 individuals who had either metabolic and bariatric surgery (sleeve gastrectomy) or were treated with GLP-1 medications between 2018 and 2023
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Others might want to try it to reduce how much alcohol they drink. There are also a growing number of people interested in microdosing GLP-1s for longevity
Our analysis of the collected data revealed that psychiatric AEs were most frequently reported in relation to diabetes ( n = 5,286, 64.15%) and weight control ( n = 332, 4.03%)