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Q12: Is AOD-9604 FDA-approved

Relative contraindications requiring careful consideration and enhanced medical supervision include history of pancreatitis, severe gastrointestinal disease including gastroparesis, diabetic retinopathy (requires ophthalmologic monitoring during therapy), severe kidney disease, history of suicidal ideation or severe depression, gallbladder disease or history of cholecystitis, and age under 18 years

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The two peptides operate through largely complementary rather than overlapping mechanisms, which suggests a potentially additive or even synergistic effect in tissue repair models