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Cultures were maintained in a humidified atmosphere of 5% CO 2 at 37C for 24 h and then incubated for the next 24-h period in DMEM-10% HS additionally containing recombinant HGF that was treated with peroxynitrite with or without trisulfide pre-treatment (see Figure 1d,f)
Research Use Only Not FDA-approved for human consumption 10
By generating mitochondrial O 2 bursts and promoting advanced glycation end product (AGE)-mediated molecular modifications, ROS impair pancreatic -cell function and induce insulin resistance [340]
Frontiers in Nutrition, 2025, DOI: 10.3389/fnut.2025.1566498,
However, any loss of lean mass matters because it can affect physical function, fracture risk and how well the body maintains weight and metabolic health over time
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