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Ozone has proposed vascular, mitochondrial and redox effects, but it remains an adjunctive and investigational therapy rather than a proven method for reversing chronic kidney disease

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Advanced additions (moderate evidence): Resveratrol or Pterostilbene (200mg or 100mg daily), Taurine (1-2g daily), Astaxanthin (6-12mg daily), Carnosine (1g daily for diabetics)