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They might start with higher doses to fill up their B12 stores

Maintaining adequate fluid intake of 1.5-2 litres daily helps prevent this

This product is supplied exclusively as a research chemical and is not intended for human consumption, clinical use, or veterinary application

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In placebo-controlled adjunctive epilepsy trials in adults receiving topiramate 200 to 1,000 mg/day, hot flashes (1% to 2%), drug-induced body odor (0% to 1%), skin disorder (1% to 2%), hyperhidrosis (1% or less), and erythematous rash (1% or less) were reported with equal or greater frequency than placebo