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143,158 There are, however, exceptions to this rule
All TrxR enzymes require an NADPH-dependent reduction step to exert their function in vivo and TrxR is a therapeutic target for cancer and infectious diseases 21,67
(1, 2) Key Takeaways Glutathione is the bodys master antioxidant, crucial for neutralizing free radicals, supporting the immune system, and protecting cells from oxidative stress
Glutathione is the liver's primary tool for "Phase II detoxification." In this phase, the liver attaches a glutathione molecule to a toxin, making it water-soluble so it can be excreted through bile or urine
In the eye, Sosne et al., Exp Eye Res 2001 reported accelerated corneal re-epithelialisation and reduced inflammation after injury, and in the central nervous system Xiong et al., J Neurosurg 2012 found that T4 initiated six hours after experimental traumatic brain injury improved sensorimotor and spatial-learning recovery while enhancing hippocampal neurogenesis
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