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These changes are likely related to significant weight loss, hormonal normalization, improved body image, and enhanced metabolic health rather than a direct pharmacological effect
The pivotal STEP (Semaglutide Treatment Effect in People with obesity) trials, which involved thousands of participants, did not identify nightmares or vivid dreams as a significant adverse event associated with semaglutide treatment
Notably, the paper reported a clear doseresponse relationship, further suggesting a pharmacological effect of GLP-1RAs on inflammatory pathways in PsO including metabolic benefits (59)
If you are flying across time zones or going on a cruise, you might prefer to take your dose a day early or a day late to avoid traveling with temperature-sensitive pens or to ensure you arent dealing with peak side effects while on a plane
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