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According to the results from in vitro and in vivo studies, tanshinone IIA pretreatment protects the liver from APAP-induced liver injury by activating Nrf2 and increasing the mRNA and protein levels of the Nrf2 target genes glutamate-cysteine ligase catalytic subunit (GCLC), NQO1, and HO-1 (Wang et al., 2016)

Consequently, sensitivity and selectivity across fluorescence, electrochemical, and ECL-based biosensors emerge from rational surface and defect engineering at the synthesis stage, underscoring the tight coupling between synthetic design and biosensing functionality, which is also directly extended to the detection of ROS

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was supported by the grant SA-111/2021 from the Hungarian Research Network