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This iron-sequestering capability is particularly important because excess free iron directly enters cells, concentrates in mitochondria, disrupts oxidative phosphorylation, catalyzes lipid peroxidation, and ultimately leads to cell death
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This translates to a relative reduction in liver fat by 37%, indicating a possible benefit in lowering liver fat accumulation
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Leucas zeylanica, which is used in traditional medicine for the treatment of GA, can also improve GA inflammation by reducing the metabolite levels through the inhibition of the AA lipoxygenase pathway (225)
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