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The administered DOX regimen (18 mg/kg cumulative dose) successfully induced consistent biochemical and histopathological hallmarks of cardiotoxicity, characterized by a significant rise in serum CK-MB, LDH, and troponin I levelsclear indicators of cardiomyocyte membrane damage and leakage of intracellular enzymes

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The figure below shows the fractions of the different acid forms (H 2 A, HA - and A 2- for twoprotic acids) in aqueous solutions at varying pH : Definition of organic compounds Hydrocarbon: An organic compound consisting entirely of hydrogen and carbon