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Heres when it may not be a safe choice: You or a close family member has had medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia syndrome type 2 (MEN 2)

Some researchers have even explored cycling between compounds as a strategy for overcoming persistent plateaus, though this approach lacks formal study data and should be considered experimental

Darkened skin patches A B12 shortage can affect melanin activity, causing darker areas near the mouth or eyes

That said, most people who think they have severe needle phobia can overcome it with proper desensitization techniques and the right injection supplies

Prefer not to be on permanent medication but accept it may be necessary Either chronic treatment or strategic cycling depending on financial capacity