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A major open question at this point is how the spending impact of these drugs might compare to the avoided cost of alternative treatments

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Epidemiological evidence has increasingly suggested that metformin, a commonly prescribed medication for type 2 diabetes, protects against the development of neurodegenerative diseases [23]

The study protocol was approved by the ethics committee of Louisiana State Health Sciences Center-Animal Care Committee (Animal Care protocol number P-15-006), and all the methods were carried out following the approved guidelines