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There are also still some unknowns about GLP-1s and how they work in the body

Clinical studies show oral and injectable semaglutide achieve comparable weight losstypically 10-15% of body weight over 68 weekswhen dosed appropriately

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Other patients also experienced clinical improvements, including a 6 year old boy with severe diabetes, ketosis (accumulation of ketones, a term first used by the German chemist Leopold Gmelin - figure 5), heavy glycosuria and malnutrition (de Levia, Brugus, de Leiva-Prez)

Reduced Caloric and Fiber Intake Patients on GLP-1 medications often eat significantly less food due to the medication's appetite-suppressing effects